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Cardiovascular Center

Kevin Regner Lab

聽The primary goal of the Regner laboratory is to investigate the cellular, molecular, and genetic mechanisms involved in ischemic acute kidney injury (AKI) and kidney repair.聽聽

kevinregner

Kevin R. Regner, MD, MS, FASN

Chief and Professor, Department of Medicine
kregner@mcw.edu

Current projects include:

Activator of G Protein Signaling 3 in Ischemic Renal Injury. The objective of this study is to characterize the role of Activator of G protein signaling 3 (AGS3), a novel non-receptor regulator of G-protein function, in renal tubular regeneration following ischemic AKI.

Genetic mapping and gene identification for acute kidney injury in outbred rats. The objective of this study is to identify novel genes that modulate susceptibility or resistance to AKI using a novel genetic resource, heterogeneous stock rats.

 


 

Bohan Xing, BS
Research Technologist I | 
bxing@mcw.edu

Utilizing the murine model of renal ischemia-reperfusion injury, Bohan characterizes renal injury using molecular and biochemical assays and histological analysis.

Recent Publications

  • (Li X, Ouyang T, Belcher JM, Patidar KR, Cullaro G, Asrani SK, Wadei HM, Simonetto DA, Regner KR, Dageforde LA, Przybyszewski EM, Wilechansky RM, Sharma P, Ufere NN, Duarte-Rojo A, Wahid NA, Orman ES, St Hillien SA, Robinson JE, Chung RT, Allegretti AS, I on behalf of the HRS-HARMONY research collaborative.) Liver Transpl. 2024 Nov 01;30(11):1106-1115 PMID: 39073567 SCOPUS ID: 2-s2.0-85200148889 07/29/2024

  • (Koratala A, Regner KR.) Liver Transpl. 2024 Oct 01;30(10):E38-E39 PMID: 38899942 SCOPUS ID: 2-s2.0-85204099158 06/20/2024

  • (Cama-Olivares A, Ouyang T, Takeuchi T, St Hillien SA, Robinson JE, Chung RT, Cullaro G, Karvellas CJ, Levitsky J, Orman ES, Patidar KR, Regner KR, Saly DL, Sawinski D, Sharma P, Teixeira JP, Ufere NN, Velez JCQ, Wadei HM, Wahid N, Allegretti AS, Neyra JA, Belcher JM, HRS-HARMONY Consortium.) Kidney360. 2024 Sep 30 PMID: 39348201 09/30/2024

  • (Ma AT, Allegretti AS, Cullaro G, Ouyang T, Asrani SK, Chung RT, Przybyszewski EM, Wilechansky RM, Robinson JE, Sharma P, Simonetto DA, Jalal P, Orman ES, Wadei HM, St Hillien SA, Saly D, Ufere NN, Dageforde LA, Regner KR, Belcher JM, Patidar KR, from the HRS Harmony Consortium.) Aliment Pharmacol Ther. 2024 Sep;60(6):778-786 PMID: 39010302 PMCID: PMC11349455 07/16/2024

  • (Koratala A, Paudel HR, Regner KR.) Am J Med Open. 2023 Dec;10:100051 PMID: 39035249 PMCID: PMC11256268 07/22/2024

  • (Koratala A, Paudel HR, Regner KR.) American Journal of Medicine Open. 2023 Dec;10: 2667-0364 10/01/2023

  • (Patidar KR, Belcher JM, Regner KR, St Hillien SA, Simonetto DA, Asrani SK, Neyra JA, Sharma P, Velez JCQ, Wadei H, Nadim MK, Chung RT, Seethapathy R, Parada XV, Ouyang T, Ufere NN, Robinson JE, McLean Diaz P, Wilechansky RM, Przybyszewski EM, Smith TN, Ali AA, Orman ES, Schulz P, Siddiqui SM, Shabbir R, Liu LJ, Cama-Olivares A, Flannery AH, Baker ML, Gunasekaran D, Aswine A, Issa R, Li J, Verma S, Chalmers D, Varghese V, Lam W, Mohamed M, Kovacic R, Gaddy A, Attieh RM, Cortes P, Semnani S, Wang L, Khemichian S, Allegretti AS, from the HRS-HARMONY consortium.) J Hepatol. 2023 Dec;79(6):1408-1417 PMID: 37517455 PMCID: PMC10807505 SCOPUS ID: 2-s2.0-85171850314 07/31/2023

  • (Swanson M, Yun J, Collier DM, Seif C, Yang CY, Regner KR, Park F.) Am J Physiol Renal Physiol. 2023 Aug 01;325(2):F248-F261 PMID: 37348027 SCOPUS ID: 2-s2.0-85165546515 06/22/2023

  • (Griffin C, Asrani SK, Regner KR.) Adv Kidney Dis Health. 2023 Jul;30(4):307-314 PMID: 37389536 06/30/2023

  • (Velez JCQ, Karakala N, Tayebi K, Wickman TJ, Mohamed MMB, Kovacic RA, Therapondos G, Kanduri SR, Allegretti AS, Belcher JM, Regner KR, Wentowski C.) Kidney360. 2023 Apr 01;4(4):e448-e456 PMID: 36763632 PMCID: PMC10278824 SCOPUS ID: 2-s2.0-85161650241 02/11/2023

  • (Miller B, Regner K, Sorokin A.) Biochemical and Biophysical Research Communications. 7 May 2022;603:69-74 SCOPUS ID: 2-s2.0-85125835040 05/07/2022

  • (Miller B, Regner K, Sorokin A.) Biochem Biophys Res Commun. 2022 May 07;603:69-74 PMID: 35278882 PMCID: PMC8969123 SCOPUS ID: 2-s2.0-85125835040 03/13/2022

Publications of from the

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