Lisa Ann Cirillo, PhD

Associate Professor; Assistant Dean for Basic Science Curriculum

Locations

Cell Biology, Neurobiology and Anatomy

Contact Information

Education

PhD, University of Illinois at Chicago, 1996
Postdoctoral, Brown University and Fox Chase Cancer Center

Research Interests

Molecular mechanisms underlying liver development and function, with a particular focus on the role played by chromatin structure in the transcriptional regulation of liver genes.

(Nghiem-Rao TH, Pfeifer C, Asuncion M, Nord J, Schill D, Pulakanti K, Patel SB, Cirillo LA, Rao S.) Sci Rep. 2021 Jun 11;11(1):12386 PMID: 34117281 PMCID: PMC8196029 SCOPUS ID: 2-s2.0-85107825189 06/13/2021
(Schill D, Nord J, Cirillo LA.) Biochem Cell Biol. 2019 Apr;97(2):118-129 PMID: 30142277 08/25/2018
(Guillen-Ahlers H, Rao PK, Levenstein ME, Kennedy-Darling J, Perumalla DS, Jadhav AY, Glenn JP, Ludwig-Kubinski A, Drigalenko E, Montoya MJ, Göring HH, Anderson CD, Scalf M, Gildersleeve HI, Cole R, Greene AM, Oduro AK, Lazarova K, Cesnik AJ, Barfknecht J, Cirillo LA, Gasch AP, Shortreed MR, Smith LM, Olivier M.) Genomics. 2016 Jun;107(6):267-73 PMID: 27184763 PMCID: PMC5017017 05/18/2016
(Yalley A, Schill D, Hatta M, Johnson N, Cirillo LA.) J Biol Chem. 2016 Apr 15;291(16):8848-61 PMID: 26929406 PMCID: PMC4861452 03/02/2016
(Mounce BC, Tsan FC, Kohler S, Cirillo LA, Tarakanova VL.) Virology. 2011 Dec 20;421(2):167-72 PMID: 22018782 PMCID: PMC3210866 SCOPUS ID: 2-s2.0-80355146848 10/25/2011
(Mounce BC, Tsan FC, Droit L, Kohler S, Reitsma JM, Cirillo LA, Tarakanova VL.) Virology. 2011 Nov 25;420(2):73-81 PMID: 21943826 PMCID: PMC3204369 SCOPUS ID: 2-s2.0-80054053305 09/29/2011
(Wu CH, Chen S, Shortreed MR, Kreitinger GM, Yuan Y, Frey BL, Zhang Y, Mirza S, Cirillo LA, Olivier M, Smith LM.) PLoS One. 2011;6(10):e26217 PMID: 22028835 PMCID: PMC3197616 10/27/2011
(Kohler S, Cirillo LA.) J Biol Chem. 2010 Jan 01;285(1):464-72 PMID: 19897491 PMCID: PMC2804194 11/10/2009
(Hatta M, Liu F, Cirillo LA.) Biochem Biophys Res Commun. 2009 Feb 20;379(4):1005-8 PMID: 19146829 01/17/2009
(Cirillo LA, Barton MC.) EMBO Rep. 2008 Aug;9(8):721-4 PMID: 18617889 PMCID: PMC2515216 07/12/2008
(Horswill MA, Narayan M, Warejcka DJ, Cirillo LA, Twining SS.) Exp Eye Res. 2008 Apr;86(4):586-600 PMID: 18291368 PMCID: PMC2374753 SCOPUS ID: 2-s2.0-41049108425 02/23/2008
(Hatta M, Cirillo LA.) J Biol Chem. 2007 Dec 07;282(49):35583-93 PMID: 17923482 10/10/2007

Cirillo Lab

cirillolab

The long term goal of the Cirillo laboratory is to uncover fundamental mechanisms which underlie the complex patterns of gene expression required for appropriate liver development and function, with a specific emphasis on the influence of chromatin structure. A critical, unresolved issue in gene regulation is the means by which the chromatin that packages developmentally regulated genes is accessed and remodeled to orchestrate cell-type specific gene expression programs. This poses a significant dilemma in cells of both the developing embryo, in which much of the chromatin is still compacted, and the adult organis

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