91九色视频

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Research Bench Lab
Microbiology & Immunology
Scott Terhune, PhD

Scott S. Terhune, PhD

Professor

Locations

  • Microbiology & Immunology
    TBRC C2890

Contact Information

General Interests

Human Cytomegalovirus Host-Cell Protein Interactions During Infection

Education

PhD, Cancer Biology, Northwestern University, 2000
Postdoctoral Fellow, Proteomics/Cytomegalovirus Biology, Princeton University, 2007
Learn more about the Terhune Lab

Research Areas of Interest

  • Alzheimer's Disease
  • Cell Cycle
  • Cell Differentiation
  • Cytomegalovirus
  • Host-Pathogen Interactions
  • Neuropathogenesis
  • Proteomics
  • Viral Proteins
  • Virus Replication

Research Experience

  • Antiviral Agents
  • Cell Cycle
  • Cyclin-Dependent Kinase Inhibitor p21
  • Cytomegalovirus
  • Histone Acetyltransferases
  • Histone Deacetylases
  • Host-Pathogen Interactions
  • Protein Kinases
  • Signal Transduction
  • STAT3 Transcription Factor
  • Tumor Suppressor Protein p53

Methodologies and Techniques

  • Cell Cycle
  • DNA, Viral
  • Drug Synergism
  • Protein Interaction Mapping
  • Proteomics
  • RNA, Viral
  • Virus Replication

Leadership Positions

  • Past Chair, Faculty Career Development Committee
  • Past member, SOM and Graduate School Rank Committees
  • Scientific Advisor, AHW

Research Interests

Our research focuses on determining the molecular functions of human cytomegalovirus (HCMV) proteins during infection and disease. HCMV is a member of the beta-herpesvirus family of viruses which includes HHV-6 and 7. Infection occurs upon exposure to virus-containing body fluids, is life-long and generally asymptomatic in healthy children and adults. However, during pregnancy, HCMV infection may result in congenital birth defects including hearing loss and neurological damage. In immunologically immature or compromised children and adults, infection often results in life threatening diseases. And, increasing evidence suggestions that persistent life-long HCMV infection is associated with numerous chronic diseases including atherosclerosis, immuno-senescence, cancer and possibly Alzheimer’s Disease.

Publications

  • (Cataldo KM, Roche KL, Monti CE, Dash RK, Murphy EA, Terhune SS.) J Virol. 2025 Jan 31;99(1):e0175124 PMID: 39655950 PMCID: PMC11784020 SCOPUS ID: 2-s2.0-85216961621 12/10/2024

  • (Cataldo KM, Roche KL, Monti CE, Dash RK, Murphy EA, Terhune SS.) bioRxiv. 2024 Oct 23 PMID: 39484423 PMCID: PMC11526937 11/04/2024

  • (Monti CE, Hong SK, Audi SH, Lee W, Joshi A, Terhune SS, Kim J, Dash RK.) Am J Physiol Gastrointest Liver Physiol. 2024 Sep 01;327(3):G424-G437 PMID: 38917324 PMCID: PMC11427087 SCOPUS ID: 2-s2.0-85202790681 06/25/2024

  • (Adelman JW, Sukowaty AT, Partridge KJ, Gawrys JE, Terhune SS, Ebert AD.) bioRxiv. 2024 Aug 19 PMID: 39229072 PMCID: PMC11370344 09/04/2024

  • (Mokry RL, Monti CE, Rosas-Rogers S, Schumacher ML, Dash RK, Terhune SS.) bioRxiv. 2024 Mar 19 PMID: 38562837 PMCID: PMC10983881 04/02/2024

  • (Colina AS, Shah V, Shah RK, Kozlik T, Dash RK, Terhune S, Zamora AE.) Front Mol Med. 2024;4:1310002 PMID: 39086435 PMCID: PMC11285593 08/01/2024

  • (Womack JA, Shah V, Audi SH, Terhune SS, Dash RK.) Bioinform Adv. 2024;4(1):vbae023 PMID: 38456125 PMCID: PMC10918630 SCOPUS ID: 2-s2.0-85187381144 03/08/2024

  • (Adelman JW, Rosas-Rogers S, Schumacher ML, Mokry RL, Terhune SS, Ebert AD.) mBio. 2023 Dec 19;14(6):e0225123 PMID: 37966250 PMCID: PMC10746155 SCOPUS ID: 2-s2.0-85183165409 11/15/2023

  • (O'Brien BS, Mokry RL, Schumacher ML, Rosas-Rogers S, Terhune SS, Ebert AD.) J Virol. 2023 Oct 31;97(10):e0069623 PMID: 37796129 PMCID: PMC10653813 SCOPUS ID: 2-s2.0-85175819477 10/05/2023

  • (Shah V, Womack J, Zamora AE, Terhune SS, Dash RK.) Annu Int Conf IEEE Eng Med Biol Soc. 2023 Jul;2023:1-5 PMID: 38083755 SCOPUS ID: 2-s2.0-85179638579 12/12/2023

  • (Zarrella K, Longmire P, Zeltzer S, Collins-McMillen D, Hancock M, Buehler J, Reitsma JM, Terhune SS, Nelson JA, Goodrum F.) PLoS Pathog. 2023 Jun;19(6):e1011185 PMID: 37289831 PMCID: PMC10284425 SCOPUS ID: 2-s2.0-85163920856 06/08/2023

  • (Adelman JW, Rosas-Rogers S, Schumacher ML, Mokry RL, Terhune SS, Ebert AD.) bioRxiv. 2023 Mar 06 PMID: 36945635 PMCID: PMC10028818 03/23/2023

Publications of from the

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