91九色视频

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Physiology
Curt-Sigmund

Curt D. Sigmund, PhD

James J. Smith & Catherine Welsch Smith Professor of Physiology; Chair of Physiology; Associate Director, Cardiovascular Center

Locations

  • Basic Science Building
    573A

Contact Information

Learn more about the Curt Sigmund Laboratory

Biography

Dr. Sigmund is the James J. Smith & Catherine Welsch Smith Chair of Physiology at the 91九色视频. Dr. Sigmund previously served as Professor and Roy J. Carver Chair in Hypertension Research; Director, Chair and Department Executive Officer, Department of Pharmacology; UIHC Center for Hypertension Research at the Roy J. and Lucille A. Carver College of Medicine at the University of Iowa. He has published over 250 papers, chapters, and reviews and has trained over 50 PhD students and postdoctoral fellows many of whom hold research and faculty positions nationally and internationally. He has held numerous leadership roles in prominent societies. He recently was elected to serve a two-year term as the new Chair-Elect of the American Heart Association Council on Hypertension and is currently the Chair of the Publications Committee of the American Physiological Society (APS). He was previously Associate Editor and Editor-in-Chief for several APS journals. He served on the External Scientific Review Board of the 91九色视频 Cardiovascular Center from 2016-2017 and now serves as its Associate Director.

Research Interests

Dr. Sigmund’s major areas of research focus on central nervous system and vascular mechanisms of blood pressure regulation by the renin-angiotensin system, the transcription factor PPAR-gamma, and its downstream effectors Cullin-3/RhoBTB1, investigating these using a combination of molecular biological, genetic and physiological approaches including the generation of unique transgenic and knockout models. Dr. Sigmund’s laboratory is located within the Cardiovascular Center in the Health Research Center and Medical Education buildings.

Publications

  • (Ziegler AA, Lawton SBR, Fekete EM, Brozoski DT, Wagner VA, Grobe CC, Sigmund CD, Nakagawa P, Grobe JL, Segar JL.) Am J Physiol Regul Integr Comp Physiol. 2025 Jan 01;328(1):R109-R120 PMID: 39548798 SCOPUS ID: 2-s2.0-85213215949 11/16/2024

  • (Lawton SBR, Wagner VA, Nakagawa P, Segar JL, Sigmund CD, Morselli LL, Grobe JL.) Hypertension. 2024 Nov;81(11):2209-2217 PMID: 39315447 PMCID: PMC11483214 SCOPUS ID: 2-s2.0-85205521844 09/24/2024

  • (Medrano S, Yamaguchi M, Almeida LF, Smith JP, Yamaguchi H, Sigmund CD, Sequeira-Lopez MLS, Gomez RA.) Am J Physiol Renal Physiol. 2024 Sep 01;327(3):F489-F503 PMID: 38991008 PMCID: PMC11460331 SCOPUS ID: 2-s2.0-85201991983 07/11/2024

  • (Mathieu NM, Tan EE, Reho JJ, Brozoski DT, Muskus PC, Lu KT, Wackman KK, Grobe JL, Nakagawa P, Sigmund CD.) Hypertension. 2024 Jun;81(6):1332-1344 PMID: 38629290 PMCID: PMC11096025 SCOPUS ID: 2-s2.0-85193429264 04/17/2024

  • (Reho JJ, Muskus PC, Bennett DM, Grobe CC, Burnett CML, Nakagawa P, Segar JL, Sigmund CD, Grobe JL.) Am J Physiol Regul Integr Comp Physiol. 2024 Mar 01;326(3):R242-R253 PMID: 38284128 PMCID: PMC11213288 SCOPUS ID: 2-s2.0-85186271298 01/29/2024

  • (Ritter ML, Wagner VA, Balapattabi K, Opichka MA, Lu KT, Wackman KK, Reho JJ, Keen HL, Kwitek AE, Morselli LL, Geurts AM, Sigmund CD, Grobe JL.) Physiol Genomics. 2024 Mar 01;56(3):265-275 PMID: 38145289 PMCID: PMC10866620 SCOPUS ID: 2-s2.0-85185200180 12/25/2023

  • (Cavallero S, Roustaei M, Satta S, Cho JM, Phan H, Baek KI, Blázquez-Medela AM, Gonzalez-Ramos S, Vu K, Park SK, Yokota T, Sumner J, Mack JJ, Sigmund CD, Reddy ST, Li R, Hsiai TK.) Sci Adv. 2024 Feb 16;10(7):eadj7481 PMID: 38354249 PMCID: PMC10866565 SCOPUS ID: 2-s2.0-85185344629 02/14/2024

  • (Sigmund CD.) Function (Oxf). 2024;5(1):zqad071 PMID: 38196837 PMCID: PMC10775765 SCOPUS ID: 2-s2.0-85182088208 01/10/2024

  • (Opichka MA, Livergood MC, Balapattabi K, Ritter ML, Brozoski DT, Wackman KK, Lu KT, Kozak KN, Wells C, Fogo AB, Gibson-Corley KN, Kwitek AE, Sigmund CD, McIntosh JJ, Grobe JL.) Sci Adv. 2023 Dec;9(48):eadg8118 PMID: 38039359 PMCID: PMC10691776 SCOPUS ID: 2-s2.0-85178323055 12/01/2023

  • (SenthilKumar G, Mathieu NM, Freed JK, Sigmund CD, Gutterman DD.) Am J Physiol Heart Circ Physiol. 2023 Oct 01;325(4):H882-H887 PMID: 37624099 SCOPUS ID: 2-s2.0-85171900302 08/25/2023

  • (Mathieu NM, Fekete EM, Muskus PC, Brozoski DT, Lu KT, Wackman KK, Gomez J, Fang S, Reho JJ, Grobe CC, Vazirabad I, Mouradian GC Jr, Hodges MR, Segar JL, Grobe JL, Sigmund CD, Nakagawa P.) Function (Oxf). 2023;4(5):zqad043 PMID: 37609445 PMCID: PMC10440998 SCOPUS ID: 2-s2.0-85168790693 08/23/2023

  • (Kumar G, Fang S, Golosova D, Lu KT, Brozoski DT, Vazirabad I, Sigmund CD.) Function (Oxf). 2023;4(5):zqad034 PMID: 37575477 PMCID: PMC10413933 SCOPUS ID: 2-s2.0-85168062439 08/14/2023

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