Jacob Bartosiak
G3 Student
Faculty Advisor
- John Corbett, PhD, Biochemistry
Locations
- Medical Scientist Training Program
Contact Information
Education
Research Interests
Type 1 and type 2 diabetes mellitus
Research Experience
91ɫƵ, 2022-present
Advisor: John Corbett, PhD
Project: Mechanisms of beta cell protection
University of Wisconsin – Madison, 2018 - 2020
Advisor: Dawn Davis, MD, PhD
Project: The role of CCK in protection from beta cell apoptosis
91ɫƵ, Summer 2017
Advisor: John Corbett, PhD
Project: Role of Src family kinases in macrophage inflammatory responses to EMCV
91ɫƵ, Summer 2016
Advisor: John Corbett, PhD
Project: Protein mispalmitoylation, ER stress, and beta cell death
Publications
Kim HT, de Souza AH, Umhoefer H, Han JY, Anzia L, Sacotte SJ, Williams RA, Blumer JT, Bartosiak JT, Fontaine DA, Baan M, Kibbe CR, & Davis DB. (2021). Cholecystokinin Suppresses β-Cell Apoptosis, Including in Human Islets in a Transplant Model. https://doi.org/10.1101/2021.03.02.433645
Baldwin AC, Naatz A, Bohnsack RN, Bartosiak JT, Oleson BJ, Hansen PA, Dahms NM, Corbett JA. Cation-Independent Mannose 6-Phosphate Receptor Deficiency Enhances β-Cell Susceptibility to Palmitate. Mol Cell Biol. 2018 Mar 29;38(8):e00680-17. doi: 10.1128/MCB.00680-17. PMID: 29378831; PMCID: PMC5879465.
Meeting Abstracts
Bartosiak JT, Gehant AL, Corbett JA. EMCV infection as a model for innate antiviral mechanisms in pancreatic beta cells. Diabetes Research Day, University of Wisconsin - Madison, Madison, WI, USA. September 2023. [Poster]
Bartosiak JT, Hansen PA, Schumacher E, Corbett JA. Innate immune activation influences transcriptional responses in pancreatic islets. Center for Immunology's 14th Annual Scientific Retreat, 91ɫƵ, Milwaukee, WI. June 2024. [Poster]
Bartosiak JT, Gehant AL, Corbett JA. The Impact of IL-1b in Islet Antiviral Responses. ADA 84th Scientific Sessions, Orlando, FL. June 2024. [Poster]
Bartosiak JT, Gehant AL, Hansen PA, Corbett JA. IL-1b inhibits encephalomyocarditis virus (EMCV) replication in pancreatic islets. Midwest Islet Club Meeting, University of Chicago, Chicago, IL. July 2024. [Oral]
Bartosiak JT and Corbett JA. EMCV infection as a model for innate antiviral mechanisms in pancreatic beta cells. Midwest Islet Club Meeting, University of Minnesota - Minneapolis, Minneapolis, MN. May 2023. [Poster]
Bartosiak JT, Banerjee A, Chen X, Omari E, Li A, Straza M, Awan M, Puckett L, Siker M, Schultz C, Erickson B, Paulson E, Hall WA. Apparent diffusion coefficient (ADC) as an Early Biomarker for tumor response to Radiation Therapy, A Meta Analysis. ASTRO Annual Meeting. San Antonio, TX. October 2022. [Poster]
General Interests
Sports, especially soccer and football, hiking, snowboarding, going to the gym, and cooking