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Zachary Smith, DO, MSc

Associate Professor

Location

  • Gastroenterology and Hepatology - Froedtert Hospital
  • 8850 William Coffey Drive
  • Milwaukee, WI 53226

Specialties

  • Gastroenterology

New & Established Patients Call

I pride myself on establishing a meaningful relationship with all patients I care for. As an interventional endoscopist, I often see patients that are referred from other gastroenterologists and physicians for complex endoscopic problems. This occasionally results in meeting the patient for the first time right before his/her procedure. I make every effort to explain the problem, and the treatment plan to the patient and his/her loved one(s) so that they understand what we propose to do and what the next steps will be. Additionally, I place a high value on multidisciplinary care and collaboration. Many patients I treat are also cared for by other specialists and in these circumstances, input from the entire treatment team is imperative to optimize patient outcomes. Further, some conditions such as pancreatic fluid collections have various treatment options that span disciplines such as hepato-pancreaticobiliary surgery and interventional radiology. Only when we discuss and plan treatment strategies in a collaborative manner, are we able to achieve the best outcomes for our patients.

Overview

Diseases and Conditions

  • Barrett's Esophagus
  • Bile Duct Cancer
  • Esophageal Cancer
  • Pancreatic Cancer
  • Pancreatitis
  • Pancreatobiliary Disease
  • Polyps
  • Bile Duct Disorders
  • Pancreatic Fluid Collections

Treatments and Services

  • Stenting of the GI Tract
  • ERCP
  • Endoscopic Ultrasound (EUS)
  • Endoscopic Mucosal Resection (EMR)
  • Interventional Endoscopy
  • Endoscopic Suturing
  • Endotherapy for Barrett's Esophagus
  • Endoscopic Management of Perforations, Leaks and Fistulas

Patients Ages Seen

  • Adult
  • Senior

Languages

  • English

Hospital Affiliations

  • Froedtert Hospital – Milwaukee
  • Zablocki VA Medical Center – Milwaukee

Board Certifications

  • Gastroenterology
  • Internal Medicine

Clinic Locations

map of clinics' locations

Biography

Dr. Smith did his Gastroenterology and Hepatology training at the 91九色视频. After pursuing subspecialty training in interventional endoscopy at Washington University School of Medicine in St. Louis, and spending three years on faculty at Case Western Reserve University School of Medicine in Cleveland, he returned to 91九色视频 in 2020 to join the faculty in the Division of Gastroenterology and Hepatology. His clinical expertise is interventional endoscopy and pancreaticobiliary disorders. Dr. Smith has extensive research interests in many fields of gastrointestinal endoscopy and his primary research focus at 91九色视频 is to design and conduct clinical trials and other high-impact studies that will help shape best practices of gastrointestinal endoscopy in the future.

Education and Training

Doctor of Osteopathic Medicine - Michigan State University College of Osteopathic Medicine - East Lansing, MI (2009)
Residency in Internal Medicine - University of Chicago Pritzker School of Medicine/NorthShore University HealthSystem - Evanston, IL (2009-2012)
Chief Resident - Internal Medicine - University of Chicago Pritzker School of Medicine/NorthShore University HealthSystem - Evanston, IL (2012-2013)
Fellowship in Gastroenterology and Hepatology - 91九色视频 Affiliated Hospitals - Milwaukee, WI (2013-2016)
Fellowship in Interventional Endoscopy - Washington University School of Medicine - St. Louis, MO (2016-2017)
Master of Science (MSc) in Clinical Trials - University of Oxford - Oxford (2022-2024)

Publications

  • (Wani S, Zhang J, Foster LD, Durkalski-Mauldin V, Elmunzer BJ, Stent Versus Indomethacin (SVI) Study Group.) Clin Gastroenterol Hepatol. 2025 Jan;23(1):175-178.e2 PMID: 39089516 SCOPUS ID: 2-s2.0-85203410003 08/02/2024

  • (Bishay K, Meng ZW, Khan R, Gupta M, Ruan Y, Vaska M, Iannuzzi J, O'Sullivan DE, Mah B, Partridge ACR, Henderson AM, Guo H, Samnani S, DeMarco M, Yuan Y, Elmunzer BJ, Keswani RN, Wani S, Smith ZL, Bridges RJ, Heitman SJ, Hilsden RJ, Brenner DR, Leontiadis GI, Forbes N.) Gastroenterology. 2024 Nov 07 PMID: 39515394 11/13/2024

  • (Bishay K, Ruan Y, Barkun AN, Chen YI, Singh A, Hookey L, Arya N, Calo NC, Grover SC, Siersema PD, Thosani N, Darvish-Kazem S, Siegal D, Bass S, Cole M, Lei Y, Li S, Mohamed R, Turbide C, Chau M, Howarth M, Cartwright S, Koury HF, Nashad T, Meng ZW, Tepox-Padrón A, Kayal A, González-Moreno E, Brenner DR, Smith ZL, Keswani RN, Elmunzer BJ, Wani S, Bridges RJ, Hilsden RJ, Heitman SJ, Forbes N.) Am J Gastroenterol. 2024 Nov 01;119(11):2317-2325 PMID: 39495582 11/04/2024

  • (Han S, Zhang J, Durkalski-Mauldin V, Foster LD, Serrano J, Coté GA, Bang JY, Varadarajulu S, Singh VK, Khashab M, Kwon RS, Scheiman JM, Willingham FF, Keilin SA, Groce JR, Lee PJ, Krishna SG, Chak A, Slivka A, Mullady D, Kushnir V, Buxbaum J, Keswani R, Gardner TB, Wani S, Edmundowicz SA, Shah RJ, Forbes N, Rastogi A, Ross A, Law J, Yachimski P, Chen YI, Barkun A, Smith ZL, Petersen BT, Wang AY, Saltzman JR, Spitzer RL, Spino C, Elmunzer BJ, Papachristou GI, SVI Study Group.) Gastrointest Endosc. 2024 Oct 09 PMID: 39389431 SCOPUS ID: 2-s2.0-85208994022 10/11/2024

  • (Elmunzer BJ, Zhang J, Coté GA, Edmundowicz SA, Wani S, Shah R, Bang JY, Varadarajulu S, Singh VK, Khashab M, Kwon RS, Scheiman JM, Willingham FF, Keilin SA, Papachristou GI, Chak A, Slivka A, Mullady D, Kushnir V, Buxbaum J, Keswani R, Gardner TB, Forbes N, Rastogi A, Ross A, Law J, Yachimski P, Chen YI, Barkun A, Smith ZL, Serrano J, Petersen B, Wang AY, Saltzman JR, Spitzer RL, Ordiah C, Spino C, Foster LD, Durkalski-Mauldin V, SVI Study Group*.) Am J Gastroenterol. 2024 Aug 27 PMID: 39207308 SCOPUS ID: 2-s2.0-85202550525 08/31/2024

  • (Bishay K, Ruan Y, Barkun AN, Chen YI, Singh A, Hookey L, Arya N, Calo NC, Grover SC, Siersema PD, Thosani N, Darvish-Kazem S, Siegal D, Bass S, Cole M, Lei Y, Li S, Mohamed R, Turbide C, Chau M, Howarth M, Cartwright S, Koury HF, Nashad T, Meng ZW, Tepox-Padrón A, Kayal A, González-Moreno E, Brenner DR, Smith ZL, Keswani RN, Elmunzer BJ, Wani S, Bridges RJ, Hilsden RJ, Heitman SJ, Forbes N.) Am J Gastroenterol. 2024 Jul 05 PMID: 38976522 SCOPUS ID: 2-s2.0-85200219086 07/08/2024

  • (Elmunzer BJ, Palsson OS, Forbes N, Zakaria A, Davis C, Canakis A, Qayed E, Bick B, Pawa S, Tierney WM, McLeod CG, Taylor J, Patel H, Mendelsohn RB, Bala G, Sloan I, Merchant AA, Smith ZL, Sendzischew Shane MA, Aroniadis OC, Ordiah CO, Ruddy JM, Simren M, Tack J, Drossman D, Rome Foundation Research Institute and the North American Alliance for the Study of Digestive Manifestations of COVID-19.) Clin Gastroenterol Hepatol. 2024 May;22(5):1098-1107.e3 PMID: 37995983 SCOPUS ID: 2-s2.0-85180336940 11/24/2023

  • (Elmunzer BJ, Foster LD, Serrano J, Coté GA, Edmundowicz SA, Wani S, Shah R, Bang JY, Varadarajulu S, Singh VK, Khashab M, Kwon RS, Scheiman JM, Willingham FF, Keilin SA, Papachristou GI, Chak A, Slivka A, Mullady D, Kushnir V, Buxbaum J, Keswani R, Gardner TB, Forbes N, Rastogi A, Ross A, Law J, Yachimski P, Chen YI, Barkun A, Smith ZL, Petersen B, Wang AY, Saltzman JR, Spitzer RL, Ordiah C, Spino C, Durkalski-Mauldin V, SVI Study Group.) Lancet. 2024 Feb 03;403(10425):450-458 PMID: 38219767 PMCID: PMC10872215 SCOPUS ID: 2-s2.0-85183679654 01/15/2024

  • (Smith ZL, Thorgerson AM, Dawson AZ, Wani S.) Dig Dis Sci. 2023 Dec;68(12):4439-4448 PMID: 37863992 SCOPUS ID: 2-s2.0-85174546982 10/21/2023

  • (Thalji SZ, Fernando D, Dua KS, Madhavan S, Chisholm P, Smith ZL, Aldakkak M, Christians KK, Clarke CN, George B, Kamgar M, Erickson BA, Hall WA, Evans DB, Tsai S.) Ann Surg. 2023 Dec 01;278(6):e1224-e1231 PMID: 37078282 SCOPUS ID: 2-s2.0-85176508848 04/20/2023

  • (Thalji SZ, Kamgar M, George B, Aldakkak M, Christians KK, Clarke CN, Erickson BA, Hall WA, Tolat PP, Smith ZL, Evans DB, Tsai S.) Ann Surg Oncol. 2023 May;30(5):3022 PMID: 36877324 SCOPUS ID: 2-s2.0-85152164746 03/07/2023

  • (Rivas A, Pherwani S, Mohamed R, Smith ZL, Elmunzer BJ, Forbes N.) Expert Rev Gastroenterol Hepatol. 2023;17(11):1101-1116 PMID: 37899490 SCOPUS ID: 2-s2.0-85175702275 10/30/2023

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